That’s why you create a backup deadman’s switch.

You wanted to ruin your company? Why?

If you need to reinstall your OS you don’t have to mess with the home drive. I use Linux for work and some of my clients actually require all data to be stored on a separate disk or partition from the applications. It also makes your backup strategy simpler and is transparent to you as a user.

2TB is too much space for an OS disk, especially since you’re not going to dual boot, so might as well get a bigger data directory and speed.

My workstation is a PCIE Gen 4 Threadripper. I’ve got a multifunction card with a couple 2TB Gen 3 NVMe drives that I striped and the bandwidth is identical to a single Gen4 4TB NVMe. Obviously you’d need a backup strategy to handle the case of a drive failing but that is true no matter what.

My workstation runs Ubuntu 22.04 with an AMD GPU, but I use an NVIDIA GPU (A4000 which is basically a 3070) for VFIO virtual machines, mostly windows. I did try Debian 12 vm with VFIO and had zero issues getting the Nvidia card set up. My VMs have secure boot /TPM enabled so no problems there either. I don’t remember the steps I took but basically disable secure boot in bios, install the proprietary driver, update the kernel, reenable secure boot. Debian was the easiest Linux distribution I tried to get set up. I also tried Ubuntu 23.10 and that worked ok. I think Fedora was OK but cannot remember. Bazzite surprisingly was a fail.

Also when all else fails, check the arch wiki. Obviously not tuned to Debian but generally most things you can figure out and the documentation is top notch.

Also wanted to mention if you’re not striping those Firecudas, definitely assign one of them to your home directory. If you do stripe, I’d create a 3.5TB home directory and leave 500 GB for / and your swap file.

Good luck.

ETA: in my experience, drivers either work right away or not at all so good news is that if your setup fails, it should fail fast, unlike windows that tries to find a workaround for janky configurations.