

The science behind DNA profiling is grossly overstated. it doesn’t sequence a full genome and is often using partial/degraded samples and relies entirely on statistical differences. In probability games, there’s no such thing as certainty…
In addition since 2010 anyone using “standard molecular biology techniques such as PCR, molecular cloning, and recently developed whole genome amplification (WGA), enable anyone with basic equipment and know-how to produce practically unlimited amounts of in vitro synthesized (artificial) DNA with any desired genetic profile.” and there have been a plethora of new tools/techniques which make doing that even easier…
The context for the DEFUSE program is that SARS-cov-1 was of pretty significant concern that it could mutate into a global pandemic similar to the Cov-2 pandemic that actually happened. The program was funded to investigate, learn and prepare for what were predicted to be some of the more dangerous possible mutations.
The “smoking gun” here is all correlation. Saying “they predicted correctly what was dangerous and were proactively studying it” is not a good argument for causation.
However, the theory that I haven’t seen well debunked/studied is that improper handling/disposal of dead viruses/plasmids/etc. increased the risk of/allowed for recombinants with the endemic Cov strain resulting in those mutations of greatest concern… Have you come across anything on that?